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Targeting Astrocytes for Alzheimer’s Treatment
QPS Neuro
graphic illustration of astrocytes, brain glial cells
A team of South Korean scientists at the Institute for Basic Science have made a groundbreaking discovery about the role that astrocytes may play in Alzheimer’s disease (AD). The team of researchers, led by Director C. Justin Lee, uncovered a mechanism by which astrocytes in the brain absorb high levels of acetates, which in turn …
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Targeting Microglia to Reverse Damage from Aging
QPS Neuro
Brain cells - astrocytes, pyramidal neurons, microglia cells
Researchers at Trinity Biomedical Sciences Institute (TBSI) have discovered a link between the presence of specialized immune cells, called microglia, and age-related neurological diseases. In their study, the scientists from TBSI and the University of Maryland School of Medicine observed that as the brain ages, cellular debris accumulates inside autofluorescent microglia, slowing their functioning and …
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Study Challenges Assumptions About Female Mouse Behavior
QPS Neuro
The gendered bias in research has a real-world impact: focus on male over female mice of a mouse model means that the female brain is less understood. This research gap results in the misdiagnosis of mental and neurological conditions in women, inadequate treatment, increased medication side effects, and more. Beginning to shift from male mice to female mice could mean better outcomes and treatment options — not just for women, but for everyone.
Neuroscience research has long relied on the use of mouse models as a controllable way to study the brain, model human diseases and disorders, research behavior, and develop new therapies. And this research has historically and significantly favored male mice over female mice due to the belief that female mice’s hormonal cycles made their behavior …
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Huntington’s Disease and the Striatum: A Breakthrough
QPS Neuro
nerve cells and viruses
Huntington’s disease is a rare and fatal neurodegenerative disease caused by a genetic mutation that destroys brain cells in the basal ganglia, resulting in progressive motor, cognitive, and emotional impairments. Recent research breakthroughs out of MIT are shedding light on how this disease affects the striatum, a crucial part of the basal ganglia responsible for …
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Newly Identified Schizophrenia Treatment Target Offers Hope
QPS Neuro
graphic illustration, two faces facing opposite directions, more faces in background, multi-colored
Schizophrenia is a chronic and severe psychiatric disorder that requires lifelong treatment. While schizophrenia does not have a cure, the most common and successful method of treating and managing symptoms has historically been a combination of antipsychotic medications and psychotherapy. However, this treatment regimen has limitations. While antipsychotic medications are widely available and can be …
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In Vitro Services

QPS Neuropharmacology provides research services with numerous standardized cell culture systems including transgenic and non-transgenic cell lines, glial cells, primary chicken and rat peripheral and central nervous system neurons of different developmental stages and organotypic brain slices. New models are developed and validated on request.
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In Vivo Services

As a leading CRO for CNS drug development, QPS Neuropharmacology is the premier provider for services with transgenic animals. We have more than 20 years of experience in generating, characterizing, and maintaining transgenic disease models and applying them for drug testing projects.
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Ex Vivo Services

QPS Neuropharmacology's expertise lies within the field of neurodegenerative diseases. We provide a state of the art research environment (AAALAC certified) for testing and evaluating new potential treatment approaches.
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Biobank

QPS Neuropharmacology's well characterized and validated in vivo models are useful tools to push your CNS drug discovery research forward. We are happy to support your research activities with sample material from our biobank composed of various specimen derived from our in-house in vivo models.
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animal models

QPS Neuropharmacology is highly experienced in generating, characterizing, and maintaining transgenic disease models and using them for drug testing projects for more than 20 years.
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behavioral testing

QPS Neuropharmacology provides a wide range of behavioral tests for various indications. Most tests are evaluated using rater-independent digital animal tracking systems.
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histology services

QPS Neuropharmacology offers a full set of histology services ranging from collection of tissue samples to delivering study reports that contain all experimental procedures and their outcome.
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biomarkers

QPS Neuropharmacology Department of Translational Medicine offers a selection of molecular biological methods for the investigation of various diseases. The unit supports in vitro and in vivo studies performed at QPS Austria.
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