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Understanding Amyloid Formation in Huntington’s: A Breakthrough
QPS Neuro
Amyloid plaques, degradation of neural networks, Huntington's disease
Neurodegenerative disorders, such as Huntington’s disease, Alzheimer’s disease, and Parkinson’s disease, are characterized by the accumulation of protein deposits known as amyloids in the brain. Despite extensive research into the cause and toxicity of amyloids, little has been understood regarding the initial step in amyloid formation. But in a groundbreaking new study published in eLife, …
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Estriol May Repair Damage from Multiple Sclerosis
QPS Neuro
Oligodendrocytes form insulating myelin sheaths around neuron axons in the central nervous system
As of 2020, over 2.8 million people worldwide live with multiple sclerosis (MS), a debilitating chronic autoimmune disorder of the brain and spinal cord. When a person has MS, the body attacks itself — more specifically, it attacks myelin, the fatty substance that protects the nerve fibers in the brain and spinal cord. While multiple …
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Genetic Variant Protects Against Alzheimer’s Disease
QPS Neuro
Graphic illustration of DNA strand
Alzheimer’s disease is a devastating neurodegenerative disorder that affects millions of individuals worldwide. While research has made significant strides in understanding the underlying mechanisms of the disease, effective treatments remain elusive. However, a recent study published in Nature Medicine has uncovered a new genetic variant that appears to confer protection against Alzheimer’s disease. The study, …
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Role of Mammillary Body Neurons in Alzheimer’s
QPS Neuro
graphic illustration of blue neurons
Recent research conducted by MIT scientists may shed light on the involvement of lateral mammillary body neurons in the early stages of Alzheimer’s disease (AD). Researchers found that these neurons exhibit hyperactivity and are more susceptible to neurodegeneration, highlighting their potential role in the onset of cognitive decline. Using a mouse model, the team demonstrated …
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How an Autism Gene Affects Fertility
QPS Neuro
Adult hands cupping child hands holding autism awareness ribbon
A recent study by researchers at the University of California, Riverside, has identified the biological mechanism underlying premature ovarian failure (POF): a mutation in the Fragile X messenger ribonucleoprotein 1 (FMR1) gene. The FMR1 mutation is most commonly associated with Fragile X Syndrome, a leading genetic cause of intellectual impairment and autism spectrum disorder. But …
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In Vitro Services

QPS Neuropharmacology provides research services with numerous standardized cell culture systems including transgenic and non-transgenic cell lines, glial cells, primary chicken and rat peripheral and central nervous system neurons of different developmental stages and organotypic brain slices. New models are developed and validated on request.
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In Vivo Services

As a leading CRO for CNS drug development, QPS Neuropharmacology is the premier provider for services with transgenic animals. We have more than 20 years of experience in generating, characterizing, and maintaining transgenic disease models and applying them for drug testing projects.
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Ex Vivo Services

QPS Neuropharmacology's expertise lies within the field of neurodegenerative diseases. We provide a state of the art research environment (AAALAC certified) for testing and evaluating new potential treatment approaches.
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Biobank

QPS Neuropharmacology's well characterized and validated in vivo models are useful tools to push your CNS drug discovery research forward. We are happy to support your research activities with sample material from our biobank composed of various specimen derived from our in-house in vivo models.
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animal models

QPS Neuropharmacology is highly experienced in generating, characterizing, and maintaining transgenic disease models and using them for drug testing projects for more than 20 years.
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behavioral testing

QPS Neuropharmacology provides a wide range of behavioral tests for various indications. Most tests are evaluated using rater-independent digital animal tracking systems.
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histology services

QPS Neuropharmacology offers a full set of histology services ranging from collection of tissue samples to delivering study reports that contain all experimental procedures and their outcome.
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biomarkers

QPS Neuropharmacology Department of Translational Medicine offers a selection of molecular biological methods for the investigation of various diseases. The unit supports in vitro and in vivo studies performed at QPS Austria.
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