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Study Sheds Light on Autism Spectrum Disorder Pathology
QPS Neuro
crinkled paper with image of human silhouette made of different blocks of color
A new study led by a team of UCLA scientists has found that changes in the brains of people with autism spectrum disorder (ASD) are more widespread than previously thought. The study, published in Nature, found that nearly every region of the cortex is changed in some way in people with ASD, contrary to the …
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Transgenic Mouse Models May Assist with Parkinson’s Breakthrough
QPS Neuro
neural network in brain, parkinsons disease
Research in the past few decades has revealed a link between alpha-synuclein aggregates in the brain and neurodegenerative diseases such as Parkinson’s. Until recently, though, scientists have not understood how those aggregates originate and spread. But a new experimental study using transgenic mouse models may change that. Researchers are hopeful that this new understanding of …
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Animal Model May Provide Alzheimer’s Diagnosis Breakthrough
QPS Neuro
neuron network with amyloid plaques, Alzheimers disease depiction
A new biosensing technology developed by researchers from Hokkaido University and Toppan using an animal model may signal a breakthrough in early Alzheimer’s disease diagnosis. The biosensing technology developed by the team using mouse models is able to detect amyloid β (Aβ) accumulation in the brain by measuring Aβ-binding exosomes in the blood. As clinical …
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Animal Model Study Finds New Neural Signal
QPS Neuro
graphic of female hippocampus inside brain
Scientists have long wondered how the hippocampus alternates episodic memory formation and recall. While we know that these two competing processes – learning and remembering – are controlled by the hippocampus, scientists have struggled to observe how the brain knows when and how to shift from recalling past information to learning and responding to novel …
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Tau Hot Spots: A New Discovery
QPS Neuro
Pathological phosphorylation (yellow) of Tau proteins (red-orange) leads to disintegration of microtubuli in the neuron axon an aggregation of the tau proteins. The transport of synaptic vesicles (orange-violet spheres) is interrupted
Today, over 55 million people worldwide are living with Alzheimer’s disease (AD). While AD is the most common form of dementia, there is currently no cure for the disease. But a recent discovery about the role tau may play in AD represents an exciting breakthrough in our understanding of the progression of AD and other …
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In Vitro Services

QPS Neuropharmacology provides research services with numerous standardized cell culture systems including transgenic and non-transgenic cell lines, glial cells, primary chicken and rat peripheral and central nervous system neurons of different developmental stages and organotypic brain slices. New models are developed and validated on request.
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In Vivo Services

As a leading CRO for CNS drug development, QPS Neuropharmacology is the premier provider for services with transgenic animals. We have more than 20 years of experience in generating, characterizing, and maintaining transgenic disease models and applying them for drug testing projects.
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Ex Vivo Services

QPS Neuropharmacology's expertise lies within the field of neurodegenerative diseases. We provide a state of the art research environment (AAALAC certified) for testing and evaluating new potential treatment approaches.
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Biobank

QPS Neuropharmacology's well characterized and validated in vivo models are useful tools to push your CNS drug discovery research forward. We are happy to support your research activities with sample material from our biobank composed of various specimen derived from our in-house in vivo models.
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animal models

QPS Neuropharmacology is highly experienced in generating, characterizing, and maintaining transgenic disease models and using them for drug testing projects for more than 20 years.
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behavioral testing

QPS Neuropharmacology provides a wide range of behavioral tests for various indications. Most tests are evaluated using rater-independent digital animal tracking systems.
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histology services

QPS Neuropharmacology offers a full set of histology services ranging from collection of tissue samples to delivering study reports that contain all experimental procedures and their outcome.
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biomarkers

QPS Neuropharmacology Department of Translational Medicine offers a selection of molecular biological methods for the investigation of various diseases. The unit supports in vitro and in vivo studies performed at QPS Austria.
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