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ALS Mouse Models Reveal Key Changes in Astrocytes
QPS Neuropharmacology
graphic illustration of the main cells of the brain
Amyotrophic lateral sclerosis (ALS), also known as motor neuron disease or Lou Gehrig’s Disease, is a degenerative disease that impacts the nervous system. Unfortunately, there are currently no effective treatments, and most ALS patients die within three to five years of diagnosis. As researchers desperately seek treatments for this devastating illness, one type of specialized …
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Animal Models Support Research into Autism and Inflammation
QPS Neuropharmacology
chalk illustration of human brain inside head
The Mayo Clinic reports that individuals with autism spectrum disorder (ASD) tend to experience more gastrointestinal symptoms, including pain, constipation, and diarrhea, than their peers. Unfortunately, scientists have not yet established how digestive symptoms are linked to ASD. However, Harvard Medical School and MIT researchers may have found the key. These researchers worked with animal …
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Mouse Model Confirms Importance of Amyloid β Peptide in AD Research
QPS Neuropharmacology
The amyloid precursor protein (APP) being cleaved by gamma and beta secretase and setting the beta amyloid peptide free
The number of Americans living with Alzheimer’s disease is expected to nearly triple by 2060. This statistic is alarming, but researchers are constantly working to slow the disease’s progression and improve symptoms in Alzheimer’s patients. Now, Science Daily reports that experts found that blocking a specific protein could improve Alzheimer’s symptoms. The researchers used the …
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Cell Culture Models Could Help Patients with Rare Disease
QPS Neuropharmacology
scientist working with a cell culture flask
Pompe disease is a rare lysosomal storage disease, with cases estimated at only one in every 40,000 births. While an enzyme replacement treatment for Pompe disease is available, it is time-consuming and incredibly costly to today’s patients. Left untreated, this condition can lead to early death, which is why alternative treatments are so urgent. Now, …
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Could ALS Mouse Models Improve Patient Outlook?
QPS Neuropharmacology
illustration of anatomy of amyotrophic lateral sclerosis
Amyotrophic lateral sclerosis, or ALS, is a progressive neurodegenerative disease affecting up to 30,000 people in the United States, and another 5,000 people are diagnosed every year. The disease damages and kills motor neurons in the brain and the spinal cord, eventually causing muscle weakness and paralysis. While there is currently no cure for ALS, …
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In Vitro Services

QPS Neuropharmacology provides research services with numerous standardized cell culture systems including transgenic and non-transgenic cell lines, glial cells, primary chicken and rat peripheral and central nervous system neurons of different developmental stages and organotypic brain slices. New models are developed and validated on request.
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In Vivo Services

As a leading CRO for CNS drug development, QPS Neuropharmacology is the premier provider for services with transgenic animals. We have more than 20 years of experience in generating, characterizing, and maintaining transgenic disease models and applying them for drug testing projects.
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Ex Vivo Services

QPS Neuropharmacology's expertise lies within the field of neurodegenerative diseases. We provide a state of the art research environment (AAALAC certified) for testing and evaluating new potential treatment approaches.
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Biobank

QPS Neuropharmacology's well characterized and validated in vivo models are useful tools to push your CNS drug discovery research forward. We are happy to support your research activities with sample material from our biobank composed of various specimen derived from our in-house in vivo models.
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animal models

QPS Neuropharmacology is highly experienced in generating, characterizing, and maintaining transgenic disease models and using them for drug testing projects for more than 20 years.
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behavioral testing

QPS Neuropharmacology provides a wide range of behavioral tests for various indications. Most tests are evaluated using rater-independent digital animal tracking systems.
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histology services

QPS Neuropharmacology offers a full set of histology services ranging from collection of tissue samples to delivering study reports that contain all experimental procedures and their outcome.
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biomarkers

QPS Neuropharmacology Department of Translational Medicine offers a selection of molecular biological methods for the investigation of various diseases. The unit supports in vitro and in vivo studies performed at QPS Austria.
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